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Sulderm Cream 30gm Tube
Sulconazole is a well-tolerated, broad-spectrum antifungal agent used to treat superficial fungal infections like tinea cruris and tinea corporis.
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✅ Description:
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✔️ Indication of Sulderm Cream
Sulderm is a broad-spectrum antifungal medication used to treat fungal infections like tinea cruris and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis, as well as tinea versicolor. Its effectiveness in treating tinea pedis (athlete's foot) has not been established. Symptom relief generally begins within a few days of starting treatment, and noticeable clinical improvement is usually seen within a week.
✔️ Pharmacology
Sulconazole nitrate, the active ingredient in Sulderm, is an imidazole derivative that inhibits the growth of common pathogenic fungi such as Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis. It also acts against the fungus responsible for tinea versicolor, Malassezia furfur, as well as certain gram-positive bacteria. Clinical testing has shown no irritation or allergic reactions to sulconazole nitrate.
✔️ Dosage & Administration of Sulderm Cream
Apply a small amount of the solution to the affected and surrounding skin areas once or twice daily, massaging it in gently. Symptom relief is typically experienced a few days after beginning treatment, with a visible improvement in about a week. To prevent recurrence, tinea cruris, tinea corporis, and tinea versicolor should be treated for three weeks. If there is no significant improvement after four weeks, the diagnosis may need to be reconsidered.
- Pediatric Use: Safety and effectiveness in children have not been established.
- Geriatric Use: Clinical studies have not identified significant differences in responses between elderly and younger patients.
✔️ Contraindications
Sulconazole nitrate should not be used in patients with a known hypersensitivity to any of its ingredients.
✔️ Side Effects of Sulderm Cream
In clinical trials with 370 patients using Sulderm solution, no systemic side effects were reported. A small percentage (around 1%) of patients experienced localized itching, burning, or stinging, but these reactions typically did not interfere with treatment.
✔️ Pregnancy & Lactation
- Pregnancy: The US FDA classifies sulconazole nitrate as a Category C drug. Animal studies in rats have shown embryotoxicity at doses 125 times higher than those used for humans. These high doses led to prolonged labor and complications in some animals, but no teratogenic effects were observed in studies with rats or rabbits at doses up to 50 mg/kg/day. No well-controlled studies are available for human pregnancies.
- Lactation: It is unknown if sulconazole nitrate is excreted into human or animal milk.
✔️ Precautions & Warnings
- General: Sulderm is for external use only. Avoid contact with the eyes. If irritation occurs, discontinue use and seek appropriate treatment.
- Patient Information: Patients should follow the physician’s instructions for using Sulderm, apply it externally only, and avoid getting it into the eyes.
Carcinogenesis, Mutagenesis, Impairment of Fertility
Long-term studies to assess carcinogenic potential have not been conducted. In vitro testing has shown no mutagenic activity.
✔️ Storage Conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.
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